Health informatics sits at the vibrant intersection of medicine, data science, and technology, transforming how we store, analyze, and utilize health information. This rapidly evolving field empowers clinicians and researchers to uncover patterns in patient data, improve diagnostic accuracy, and personalize treatment plans without getting lost in complex databases. By turning raw medical records into actionable insights, these innovations are reshaping the future of healthcare delivery and population health management.

At Gist.Science, we bridge the gap between cutting-edge research and public understanding by curating the latest preprints from medRxiv specifically within this domain. Our team processes every new submission in this category, providing both accessible plain-language explanations and detailed technical summaries to ensure the science is clear for everyone, from policymakers to curious readers. Below are the latest papers in health informatics, freshly distilled and ready for you to explore.

📄 health informatics

Patient Attitudes Toward Artificial Intelligence in Jordanian Healthcare: A Cross-Sectional Survey Study

A cross-sectional survey of 500 patients in Jordan reveals that while there is conditional optimism regarding AI in healthcare, acceptance is heavily dependent on maintaining human physician involvement, ensuring transparency and privacy, and addressing disparities linked to education and digital literacy.

Al-Dabbas, Z., Khandakji, L., Al-Shatarat, N., Alqaisiah, H., Ibrahim, Y., Awed, T., Baik, H., Dawoud, M., Ali, R. A.-H. (…)2026-02-24
📄 health informatics

MedOS: AI-XR-Cobot World Model for Clinical Perception and Action

MedOS is a general-purpose embodied world model that bridges the gap between abstract clinical reasoning and physical intervention by utilizing a dual-system architecture to autonomously execute complex medical procedures, simulate adverse events, and democratize clinical expertise by narrowing the performance gap between junior and senior physicians.

Wu, Y. C., Yin, M., Shi, B., Zhang, Z., Yin, D., Wang, X., Wang, Y., Fan, J., Jin, R., Wang, H., Ying, K., Pang, K., Roj (…)2026-02-23
📄 health informatics

Fully Automated Systematic Review Generation via Large Language Models: Quality Assessment and Implications for Scientific Publishing

This study demonstrates that a fully automated pipeline using large language models can generate systematic reviews with citation accuracy and expert-rated quality surpassing human-authored counterparts, while simultaneously revealing critical limitations in information breadth and the urgent need for new verification standards and AI literacy in scientific publishing.

McLaughlin, L., Walz, M. S., Arries, C.2026-02-23
📄 health informatics

Machine Learning Analysis of User Sentiments in Tinnitus Management Apps

This study utilizes a graph neural network-based sentiment analysis model on over 340,000 app store reviews to identify that while therapeutic features like sound masking and sleep support drive positive user sentiment, issues regarding pricing, advertisements, and technical stability remain key areas for improvement in tinnitus management apps.

Yousaf, M. N., Anwar, M. N., Naveed, N., Haider, U.2026-02-22
📄 health informatics

Clinicians' Rationale for Editing Ambient AI-Drafted Clinical Notes: Persistent Challenges and Implications for Improvement

This study of 30 clinicians reveals that edits to ambient AI-drafted clinical notes are primarily driven by the need to correct transcription errors, ensure clinical accuracy, mitigate liability risks, and meet billing standards, highlighting the necessity for improved AI customization, integration, and institutional support to enhance human-AI collaboration.

Guo, Y., Hu, D., Yang, Z., Chow, E., Tam, S., Perret, D., Pandita, D., Zheng, K.2026-02-22
📄 health informatics

Understanding Comorbidities in Hypermobile Ehlers-Danlos Syndrome: Could a Viral Infection Unmask the Disorder?

Analysis of over 19 million US patient records reveals that individuals with hypermobile Ehlers-Danlos Syndrome face a significantly elevated risk of developing Long COVID, particularly when overlapping with autonomic or immune dysregulation, and suggests that viral infections may often unmask previously undiagnosed cases of the disorder.

Pearson, M. L., Laraway, B. J., Elias, E. R., Bilousova, G., Haendel, M. A.2026-02-17